Fingolimod for multiple sclerosis and emerging indications: appropriate patient selection, safety precautions, and special considerations

Ilya Ayzenberg, Robert Hoepner, Ingo Kleiter Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany Abstract: Fingolimod (FTY720), an immunotherapeutic drug targeting the sphingosine-1-phosphate receptor, is a widely used medication for relapsing-remitting multiple sclerosis (MS).Apart from the pivotal Phase III trials

read more

Constructing a Regional Ionospheric TEC Model in China with Empirical Orthogonal Function and Dense GNSS Observation

Using Global Navigation Satellite Systems (GNSS) observation data for developing a high-precision ionospheric Total Electron Content (TEC) model is one of the essential subjects in ionospheric physics research and the application of satellite navigation correction.In this study, we integrate the Empirical Orthogonal Function (EOF) method with the T

read more